Load center organisation

I have a large 4 level home that I am doing a little work to and I need some ideas as to where to run wires to the 2, 40 breaker load centers.

My question is, should I run all the wires from each floor to one load center? There are 2 rows of spaces on each load center, should I run each floor to one row? Or should I use the bottom 20 spaces for basement and the top 20 spaces for floor 1 on load center one and the bottom 20 spaces for floor 2 and the top 20 spaces for floor 3 on load center two?



All comments are appreciated.

Load center organisation